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In mammalian nervous systems, many different types of chemical substances, including amino acids (e.g., glutamate), monoamines (e.g., dopamine, norepinephrine), acetylcholine, peptides (e.g., substance P), serve as neurotransmitters to bind their corresponding receptors, then activate ion channels, and consequently produce ion flux 1 , thereby inducing membrane potential changes that lead to signal propagation for neurotransmission 1,2,3,4

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doi: 10.1111/j.1365-2982.2011.01677.x

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81573621), the Science and Technology Innovation Program of Hunan Province (2021RC4064), the Hunan Key Research and Development Program (No