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Similarly, in myocardial ischemia-reperfusion, 3-AB suppressed PARP1 activation, reduced infarct size, and improved cardiac function 174

Kweider N, Fragoulis A, Rosen C, Pecks U, Rath W, Pufe T, Wruck CJ (2011) Interplay between vascular endothelial growth factor (VEGF) and nuclear factor erythroid 2-related factor-2 (Nrf2): implications for preeclampsia

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Trabectedin also blocked the transcriptional activity of fused in sarcoma-C/EBP-homologous protein (FUS-CHOP) [131]

Interestingly, As 2 O 3 over a wide range of concentration (0.12.0 M) induces degradation of a key leukemogenic protein, PMLRAR, as well as the wild-type PML, thus setting up a good example of targeting therapy for human cancers