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These actions are likely due to the potential of BPC-157 to simulate vasodilatation and angiogenesis (new blood vessel formation) due to its action on peptidergic growth factors such as endothelial growth factor, Consequently, the peptide has demonstrated significant protective effects against gastric mucosal injury in rat models

It has consequently garnered a growing interest as a potential adjunctive therapy for coronavirus disease

While the evidence that it could be responsible for Guanamian ALS/PDC is still debatable after almost 50 years (Karamyan and Speth, 2008), oral administration of BMAA to macaques dose-dependently caused a motor system disorder with involvement of both the upper and lower motor neurons as well as the extrapyramidal system after 212 weeks of treatment (Spencer et al., 1987)