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Although iron metabolism abnormalities and lipid peroxidation mediated by ferroptosis are important mechanisms that regulate kidney diseases and ferroptosis-related defense mechanisms, including the system Xc-/GSH/GPX4 pathway, the mitochondrial pathway and the FSP1/CoQ 10 /NAD(P)H pathway, the specific details and crosstalk among these pathways are still not well understood

Conclusion Taken together, the results reported in the present study demonstrated that the bioaccumulation of arsenic and its methylated metabolites was organ-specific and dose-specific

doi: 10.1016/j.micinf.2011.07.007 33 HummeSReisbachGFeederleRDelecluseHJBoussetKHammerschmidtWet al

For example, microorganisms have been shown to directly interact with components of the bloodbrain barrier (BBB), leading to coagulopathy and tight junction disruption, inducing lung inflammation that results in hypoxia, and ultimately increasing BBB permeability ( In addition, the central invasion and infiltration of immune cells following viral pre-infection may serve as a trigger for NPP