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doi:10.1097/01.ALC.0000026830.27338.23 16

Dong L, Mohan R

Early intubation and mechanical ventilation are warranted in patients with a Glasgow Coma Scale (GCS) 6.5 mmol/L), or uremic symptoms

It commonly presents in the legs, hips, and sometimes arms, and is characterized by: Disproportionate fat accumulation, usually from the waist to the ankles Tenderness or pain in affected areas, often out of proportion to appearance Easy bruising Swelling that worsens during the day or with prolonged inactivity Unlike regular weight gain, lipedema fat does not respond to diet or exercise