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The most notable clinical finding of this case is the dramatic and rapid therapeutic response with apremilast, which is faster than the efficacy reported in existing literature ( Unlike cyclosporine and methotrexate, apremilast does not cause significant immunosuppression or end-organ toxicity

Studies highlight that maintaining a minimum level of exercise enhances cardiorespiratory fitness, muscle function, flexibility, balance, and mental health (Venturelli et al., 2012)