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Again, Watterson points out that this ignores the effect of the intracellular cytoplasmic aqueous milieu in which these changes take place, and which has the same density and thermal energy as its protein solute [Web reference 6]

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2.8.4 Relationship between task-induced GSH modulation and cognitive performance We estimated a GSH modulation index (GSH baseline levels subtracted from GSH levels measured during the task), and we entered the GSH modulation index from IFC and IPL as predictors in a regression model with the cognitive flexibility index as a dependent variable