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However, cardiac expression of the nicotinamide phosphoribosyl transferase (NAMPT) is also almost systematically repressed in HF models and could lead to deficient NAD biosynthesis [185,186]

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Second, despite several clinical findings supporting the effectiveness of adjuvant antioxidant and anti-inflammatory agents, further longitudinal studies and studies with a large sample are needed

2018;13: e0201077

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