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Stage 3: mild cognitive decline (early-stage Alzheimer's can be diagnosed in some, but not all, individuals with these symptoms)

The 2.5 mg starting dose is explicitly a tolerability dose in trials it was not intended to drive weight loss on its own, but to let the gut acclimate before therapeutic doses begin

This study shows that MET inhibitors suppress a mechanism of resistance to PARP inhibitors and provides preclinical evidence for combination therapy in breast and ovarian cancer