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Physical interventions such as aerobic exercise and intermittent fasting promote synaptic plasticity via metabolic reprogramming and increased BDNF expression [217219]

For preclinical research this matters, because it allows the release of growth hormone to be studied without parallel rises in stress hormones confounding the interpretation

Verdict: Best for beginners and mild skin concerns

Chronic depression, obesity, terrible sleep, raising 3 kids, startup founder/CEO grind culture behavior (and even growing up w/ excess sugar, sun exposure, junk food). Its worth remembering: Zero (@bryan_johnson) July 18, 2023 1) My body and mind were trashed in every way for 23 years