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In natural killer T-cell lymphoma (NKTCL), blocking SLC1A1-mediated glutamine addiction in tumor cells induced PD-L1 expression and inhibited CD8(+) T-cell activity 149

A clinical trial is now underway that will test whether prolonged treatment with perhexiline for 12 months will improve left ventricular hypertrophy which is the main driver of systolic dysfunction and HF [85]