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Physiologically based pharmacokinetic modeling involving nonlinear plasma and tissue binding: Application to prednisolone and prednisone in rats

Skrabalak, I

Garcia-FernandezM.SierraI.PucheJ

Of note, NNT can also operate in a reverse mode to generate NADH from NADPH and NAD + , resulting in elevated NADH/NAD + , reductive stress, and metabolic adaption