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One of the main microenvironment components that allows the development of tumor growth is the immune system

Even a slight elevation in ROS levels within cancer cells relative to that in normal cells can surpass a critical threshold, inducing cancer cell death and suppressing tumor development [9]

Neonatal hyperbilirubinemia is extremely common because almost every newborn develops an unconjugated serum bilirubin level of more than 1.8 mg/dL during the first week of life