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The half-life determines the rate at which a drug concentration rises during a constant infusion and also the rate at which the concentration falls after drug administration is stopped

Hepatocyte growth factor (HGF) is mainly produced by stromal cells of mesenchymal origin

Primary research: Mitochondrial dysfunction, Barth syndrome, heart failure, age-related mitochondrial decline Mechanism: Binds cardiolipin in the inner mitochondrial membrane, stabilizing electron transport chain function and reducing reactive oxygen species Regulatory status: FDA-approved (Forzinity) for Barth syndrome

By the 2010s, athletes adopted it for its tissue-repairing effects, supported by preclinical data