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Nouairi et al., 2009

While red light therapy uses LED arrays for broader treatment, the Remy is a Class IV therapeutic laser that delivers concentrated high-power energy deep into tissuereaching 3-5 inches deep compared to red light's 1-2 inches

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The PFKM gene spans more than 30 kb, containing 27 exons and at least 3 promoter regions.128,198 PFK deficiency is a rare autosomal, recessively inherited disorder

Rhythmic transcripts that lost rhythmicity in cKOt mice (model 2) did not present clear phase enrichment but did show higher amplitudes (Figure 1, C and D), as expected for direct BMAL1 target genes in clock-deprived animals (27)