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doi: 10.1155/2021/9949453 250 ScirA.CianfrugliaL.MinnelliC.BartoliniD.TorquatoP.PrincipatoG.et al

In AD, altered A 2A and A 1 receptor-mediated signaling modulates EAAT2 expression, AQP4 polarization, and inflammatory states, while P2X 7 receptor hyperactivation exacerbates neuroinflammation and astrocyte-mediated cell death

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