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The percent of oxidized mito-Grx1-roGFP2 in U87vIII CHCHD2 KO cells was decreased by 15.8% compared to that measured in CHCHD2 WT cells, indicating that the pool of glutathione in the mitochondrial matrix of KO cells was more reduced than the WT counterparts (Fig

doi: 10.1001/jamadermatol.2015.1187 162 GibsonGEAhmedI

Method validation All validation items were adequately assessed to guarantee that the techniques met ICH demands 37

The effect of thiols (GSH, Cys, DTT) on the reduction of cytochrome c GSH is the thiol compound of largest concentration in the cells