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However, several articles have commented on the situation, analyzed the reasons for the trials failure and discussed potential future directions for development

[PMC free article] [PubMed] [Google Scholar] 58.Vaca G, Armbula E, Monsalvo A, et al

doi: 10.1164/rccm.201601-0103OC 70 BrandenburgJMarwitzSTazollSCWaldowFKalsdorfBVierbuchenTet al

This study utilizes human faecal metagenomic data sets to perform an in-depth in silico analysis of SCFA fermentation pathways in different populations

PCS activates NADPH oxidase and the production of ROS via the protein kinase C and PI3K signaling pathways, which lead to the expression of inflammatory cytokines in renal tubular cells and the mediation of renal fibrosis [109]