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Kassar-Duchossoy L, et al

However, as the development of multi-specific protein therapeutics becomes more widespread, the potential for immune complex formation and consequent immunogenicity must be considered, as the latter can lead to both loss of pharmacodynamic activity and safety concerns

Preclinical acute toxicity is low, with reported rodent LD50 values well above any human-equivalent research dose

Genetic analysis reveals AMPK is required to support Tumor Growth in Murine Kras-Dependent Lung Cancer models

My legs did become weak yes & walking down any steps or stairs they would constantly shake, this started around 3 years ago, along with bumping into door frames & losing my balance etc