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Phytotherapy Research 2006;20(2) 120-124 156

Tumor rechallenge experiments demonstrated that mice previously cured with combination therapy were fully protected against CT26 cells but not 4T1 cells, confirming tumor antigen-specific immune memory

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Oral administration of 1,000 mg of ascorbic acid to the controls resulted in a rapid increase in plasma ascorbic acid in the first two hours with peaks between 1.80 and 3.5 mg/dL and the urinary concentration of ascorbic acid showed a maximal increase