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An improved understanding of the regulatory mechanisms in the development of cardiovascular disease may help to identify new therapeutic targets and provide beneficial effects for patients

using the Approximately 1 g of total RNA was used to prepare a small RNA library TruSeq Small RNA Sample Prep Kits (Illumina, USA)

Thus, among the black race Americans, the frequency of the gene of the enzymatic deficiency is from 0.10% to 0.11%34 with 15% of enzymatic activity related to normal 35

The resulting libraries were sequenced on an Illumina HiSeq 2500 instrument to generate strand-specific, paired-end reads of length 125 bp (HiSeq SBS Kit v4 sequencing reagents)

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