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[205] [198] [76] Phosphorylation of DAT by either kinase induces transporter internalization (non-competitive reuptake inhibition), but PKC-mediated phosphorylation alone induces the reversal of dopamine transport through DAT (i.e., dopamine efflux)

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Neurosci Biobehav Rev 144:104961

Experimental issues such as the selection of animals, volume of administration, use of anesthesia, and pH of the substance must be refined for the intranasal delivery

Genetic Findings of GSH GS deficiency is a rare disorder of glutathione (GSH) metabolism manifested in children by severe metabolic acidosis with high urinary level of 5-oxoproline (pyroglutamic acid), hemolytic anemia, and neurological events