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J of Basic Appl Zool 71:1019

In this study, we evaluate the SL and KAR recognition ability of ShHTLs and ShD14 in vitro and determine the crystal structures of different clades of ShHTLs and ShD14, providing structural insights into the evolution of their SL/KAR selectivity based on a comprehensive structural comparison

& Minich D.M

However, since NIE may release NO only inside cells, NIE may be able to reach tumors without releasing NO in the blood, liberate NO after being absorbed into the cells and exert its antitumor activity