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33 Similarly, systematic screening under ER stress conditions continues to uncover new UPR modulators that could be pharmacologically leveraged in metabolic and inflammatory pathologies

It upregulates genes for extracellular matrix proteins and growth factors and downregulates proinflammatory genes

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Alfonso, H., et al., Effect of N-acetylcysteine supplementation on oxidative stress status and alveolar inflammation in people exposed to asbestos: a double-blind, randomized clinical trial