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By temporally mapping these alterations to a post-maturational window (P12 in SMA mice), we highlight a phase in which functionally mature INs begin to fail, likely as a consequence of SMN deficiencyinduced disruption of the neuronastrocyte GGG cycle, while offering a plausible developmental origin for the cortical dysfunction observed in SMA

As consumers become increasingly mindful of their well-being, healthy choices are no longer occasional they have become part of daily life

Symptoms may develop slowly or appear quickly

Regular use of the supplement improves reproductive efficiency and the breeding condition of males during the reproductive period

This study is the first to demonstrate the genotoxic effects of other metabolites beyond methylmalonic and propionic acids and to show the protective potential effect of different antioxidants in mitigate DNA damage