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Low glutathione levels have been linked to weakened immunity and increased susceptibility to infections[1]

Similar antioxidant mechanisms of protection mediated by BVR have been reported in a model of experimental autoimmune encephalomyelitis (Liu et al., Kinase activity IGF/NF-B Biliverdin reductase exhibits theronine-serine and tyrosine kinase activity (Salim et al., 198 MKM motif of BVR allows BVR the ability to mimic the function of a receptor-like protein by interaction with upstream signaling proteins similar to growth factor receptors such as PDGFR or EGFR

Pain Physician 20 , 419427 (2017)

Nature 434 , 113118 (2005)

RNA isolation and gene expression analysis Total RNA was isolated from 100 mg of shoot tissue using RNA Plus (CAS: 9108, Takara, Otsu, Japan)