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Description

This explains why patients with normal BMI but high visceral-to-subcutaneous fat ratios can present with severe insulin resistance

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A large meta-analysis found that this flattened pattern is associated with fatigue, depression, immune dysfunction, inflammation, and obesity 3

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Targeting the mutant histone directly has proven difficult, responds Dr

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Proc Natl Acad Sci USA 110(10):38063811

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Biochim Biophys Acta Proteins Proteom 1867(10):890908

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