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The main pathway runs through the hypothalamic-pituitary-adrenal (HPA) axis and its interaction with the hypothalamic-pituitary-gonadal (HPG) axis

Dihexa essentially reactivates developmental neuroplasticity mechanisms, potentially explaining its remarkable effects on learning and memory in animal models

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And, by the time the patient awakes in the morning, the blood levels could be expected to have fallen more than they would have had the patient taken the drug at bedtime