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SARS-CoV-2 infection of airway epithelial cells

Small compounds such as PRIMA-1 (APR-017), APR-246 (Eprenetapopt), and COTI-2 restore mutant p53 to a functional state, reactivating its tumor-suppressive capabilities, with potential therapeutic uses in a variety of malignancies (Devor et al., 2021)

doi:10.3390/life11020091

In the framework of I/R injury, VEGF can promote BBB repair and protect against vascular damage (Hoseinzadeh et al., 2022)