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In contrast, the in vitro reduction of Escherichia coli RNR or PR was shown to require both active-site cysteinyl residues of glutaredoxin 1 (EcGrx1) 41,57

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However, the implementation of holistic solutions that consider synergies and trade-offs to target the United Nations' SDGs (181) and simultaneously address health and climate change challenges is restricted by the lack of action by decision-makers at both the national and global levels (189, 193196)

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[11] Obesity affects the GH axis substantially