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Impairment in consolidation of learned place preference following dopaminergic neurotoxicity in mice is ameliorated by N-acetylcysteine but not D1 and D2 dopamine receptor agonists

DeLeo V, Petraglia F, Bruno MG, Lanzetta D, Inaudi P, DAntona N

2017 June 21

This suggests that neuronal degeneration may lead to local release of iron, which is subsequently scavenged and stored by microglia to maintain brain iron homeostasis (346)

Fatal outcomes documented at therapeutic doses: The first documented case of a pregnant woman dying from liver failure after taking normal, recommended doses of acetaminophen