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This absence of consistency complicates the comparison of research findings, the determination of optimal dosage ranges, and the anticipation of clinical efficacy

[] In pathological states such as HF, repressive marks such as H3K9me3 accumulate on metabolic gene promoters, leading to the coordinated downregulation of biogenesis, oxidative phosphorylation, and potentially dynamic genes

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Initial effects like improved sleep and energy typically appear within 2-4 weeks