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The interplay between ethanol-induced alterations in the endocannabinoid system and synaptic plasticity highlights the complexity of the neurobiological changes associated with chronic alcohol use

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Monje F.J., Cabatic M., Divisch I., Kim E.J., Herkner K.R., Binder B.R., Pollak D.D

Our results show that the alternative disordered E-domains affect distinct aspects of proIGF-1s regulation including protein stability, localisation and secretion