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Its precise, high-dose combination of *thiamine*, *pyridoxine*, and *cyanocobalamin* makes it a leader in its class for therapeutic intervention

This layout allows teams to map triple-receptor kinetics and track rapid weight-related signaling shifts during the exact same observation window

What they found: In normal obese mice: AOD-9604 reduced body fat by 21 % vs placebo, hGH by 24 % The AOD-9604 effect was fully dependent on the 3-adrenergic receptor , in knock-out mice no effect The hGH effect was partly independent of 3-AR , in knock-out mice there was still ~10 % fat reduction AOD-9604 did not raise IGF-1 (control level), whereas hGH raised IGF-1 by 80 % No changes in growth, organ weights (except adipose tissue), fasting insulin Why it matters: The study provided the mechanistic basis for AOD-9604 and confirmed the key business hypothesis: it is possible to separate the lipolytic effect of GH from its growth effect

Like all raw cosmetic actives, this product should be incorporated into a finished formulation at the recommended usage rate

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