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The mechanisms and drug targets being explored are diverse

As early changes that disrupt cellular homeostasis and promote genomic instability, epigenetic modifications are now considered first hits in tumorigenesis, particularly through the altered expression of TSGs, which are often epigenetically silenced rather than mutated (Bouyahya et al

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When the body lacks sufficient B12, one of the most debilitating symptoms is extreme fatiguea profound exhaustion that differs markedly from ordinary tiredness