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Cagrilintide is also studied in combination with semaglutide (the investigational pairing known as CagriSema ), where trials have reported substantial weight reductions beyond either agent alone [5] [6]

Unlike metformin, which has a well-documented association with reduced vitamin B12 absorption, tirzepatide has not demonstrated a similar pharmacological mechanism that would directly interfere with B12 metabolism or absorption in the terminal ileum

Vitamin B12 (Adenosylcobalamin) Supports energy metabolism and red blood cell formation

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