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likewise, an interferon (IFN) regulatory factor 5 (IRF5) polymorphism that enhances proinflammatory TLR signaling is associated with MAS in sJIA 30 , further linking endosomal Munc13-4 to eTLR-driven systemic inflammation

7, 2016, p

Selective P2X3 antagonist Eliapixant (BAY 1817080): ATP-dependent P2X3 receptors play a fundamental role in nerve fiber sensitization and pathological pain pathways