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Investigations Complete workup for a source of fever including multiple sets of blood cultures, respiratory viral panel, two malarial blood films (thin and thick), dengue serology, viral hepatitis serology (A, B, C and E) and HIV screen were negative with a relatively low C-reactive protein of 10.9 mg/L and normal serum lactate

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As shown in Figures 1FH, PAS and H&E staining showed mesangial matrix accumulation (black arrows) and enlarged glomerular volume (red arrows) in DKD mice, which were attenuated by HU treatment

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