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Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells

It's creating a ton of energy, but it's also filling the room with toxic, suffocating exhaust (oxidative stress)

184 Astrocytic reactivity in diffuse brain injury is quite distinct from full blown reactive astrogliosis in focal TBI

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PLCs are classically coupled to GPCRs, therefore we tested orphan GPCR Olfr39 overexpressing cells identified in the same screen [32] and observed the prototypical pattern of Ms4a15 OE in viability, Ca 2+ , and lipid regulation (Supplementary Fig