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A casecontrol study in the USA (Chan et al., 2009) examined ASB consumption and adenocarcinoma of the exocrine pancreas, reporting some indication of potential effect modification by diabetes: risk was elevated among those without diabetes but not among those with diabetes

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Surprisingly, multiple ALS-causative mutations in FUS/TLS increase FUS/TLS interaction with SMN, thereby affecting the normal function of SMN by both reducing Gem bodies and changing steady-state levels of some snRNAs in transgenic mouse tissues and patient fibroblasts expressing mutant FUS/TLS

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