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doi:10.1126/science.125.3253.884

The best clinical result was 2.6 kilograms over 12 weeks, roughly 5.7 pounds

If a person experiences severe diarrhea or blood in stool, it can lead to nutrient loss and further complications

Whether future small-molecule programs can achieve dual or triple receptor agonism in an oral formulation remains one of the most important questions in the field