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Concluding remarks It should be noted that glutamate metabolism is exceedingly complex and highly compartmentalized

Garcia Lopez M, Baron JA, Omsland TK, Sgaard AJ, Meyer HE

Front Genet 3:195 Parada C, Marians K (1991) Mechanism of DNA A protein-dependent pBR322 DNA replication

Trophic factor-induced intracellular calcium oscillations are required for the expression of postsynaptic acetylcholine receptors during synapse formation between Lymnaea neurons

This antitumor effect could be reversed by aspartate supplementation [26], reinforcing that the presence of other metabolites (in this case, another amino acid) in the TME can influence the effects of a single one in tumor biology