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This type of compound undergoes GST-catalyzed breakdown to release locally cytotoxic metabolites and thereby attenuate off target adverse side effects

10.1371/journal.pone.0157113 PLoS One 2 AleshinV

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When immune cells respond to an infectious microbe, it has been shown that human leukocytes, neutrophils, in particular, possess the ability to transport the oxidized form of vitamin C across its membrane to use as a defense mechanism against ROS produced during an immune response [25]