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159,163166 Tissue transglutaminase whole body distribution and biological functions Before describing gluten peptide distribution in tissues and organs, it is important to remember that tTG is ubiquitous in the human body

Reference Edwards, Buono, Fordham, Skipsey, Brazier, Dixon and Cummins2005

The accumulation of LCACs during mitochondrial FAO disorders can inhibit the activity of PPAR/PGC1, destroy the regeneration of peroxisomes, lead to increases in BCAA and ROS levels, and activate the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway

The activity of this proton pump induces H + extrusion, causes membrane potential hyperpolarization, induces K + in channels while deactivating K + out channels, and uptakes charged solutes and water, leading to the guard cells to swell and open (Schroeder and Neher, 1987)

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