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Recent advances in single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, spatial proteomics, and patient-derived models have begun to reshape our understanding of chemoresistancenot as a static trait, but as a dynamic and heterogeneous process shaped by both tumor cell plasticity and microenvironmental cues

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10.1016/j.ijbiomac.2024.133794 178 ZengB.ZhangS.XuH.KongF.YuX.WangP.et al

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