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In Vitro Evidences for Ethanol-Inducible CYP2E1 and ADH Activity Several in vitro models have been established to study the adverse effects of ADH and CYP2E1 in liver cells

Recent studies on phase 1 clinical trials using, Elamipretide, a mitochondrial-targeted drug, have shown a positive effect on visual function without adverse effects (Mettu et al., 2022)