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Clin Exp Optom 91(3):207225 Horng CT, Ma JW, Shieh PC (2021) Improvement of presbyopia using a mixture of traditional Chinese herbal medicines, including Cassiae Semen, wolfberry, and Dendrobium huoshanense

Research reveals that platinum-resistant HGSOC cells often exhibit suppression of Homologous Recombination (HR) repair pathways, while alternative repair mechanisms, such as Non-Homologous End Joining (NHEJ), are activated ( Single-cell RNA sequencing has revealed specific drug-resistant cell subpopulations in HGSOC that promote their growth and drug resistance through interactions with fibroblasts and endothelial cells in the tumor microenvironment ( 3.3 Apoptosis and autophagy In the apoptotic pathways of tumor cells and HGSOC cells, key proteins such as the Bcl-2 family, p53, and caspases play crucial roles ( p53, as a tumor suppressor, promotes apoptosis by inducing the expression of apoptosis-related genes, particularly in cases of DNA damage ( Autophagy plays a dual role in the drug resistance of tumor cells and HGSOC

Rhizoma smilacis glabrae protects rats with gentamicin-induced kidney injury from oxidative stress-induced apoptosis by inhibiting caspase-3 activation

doi: 10.1016/j.redox.2025.103543 76 RongYHuangLYiKChenHLiuSZhangWet al

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