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10.1007/s11064-015-1776-x 31 DangT

Only 3001,200 milligrams of alpha lipoic acid daily helps improves insulin sensitivity and reduces symptoms of diabetic neuropathy

Cell viability and proliferation were determined using the CCK-8 kit (MA0218, Meilun) at 0, 24, 48, 72, and 96 h post seeding, as described previously ( t -test

PCR data showed that 200 M H 2 O 2 treatment upregulated IL-1, MMP13, Collagen-X, Caspase3, and Caspase9 at mRNA level in chondrocytes, while metformin significantly attenuated these H 2 O 2 exposure induced increases (Fig