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Preserving muscle while losing fat is a major therapeutic goal in obesity medicine, as loss of muscle mass can worsen metabolic function and long-term outcomes

In malignant proliferating cells dominated by glycolysis, the upregulation of glutamine metabolism promotes energy metabolism via the modulation of TCA cycle and provides raw materials for lipid and amino acid delivery as well as biosynthesis of purines and pyrimidines, which ultimately promotes tumor growth by facilitating cell proliferation and inhibiting cell apoptosis ( The upregulation of glutamine metabolism has been extensively studied in many types of cancer and its very critical for the pathogenesis of cancers, which renders it a well-known target for cancer therapy

Ultrasound of the bladder showing a stone causing recurrent UTI 4

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53 These findings suggest that SCFAs may exert a dual modulatory effect on macrophage activation