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Combined cistromic and transcriptomic analyses have shown that AR expressed in myofibers controls the expression of transcription factors and genes involved in glycolysis, fatty acid metabolism, polyamine biosynthesis, reactive oxygen species (ROS) scavenging and cytoskeleton remodeling of skeletal muscle

doi: 10.1016/S2215-0366(15)00309-0 95 GillJVythilingamMPageGG

It binds directly to IGF-1 receptors in muscle, bone, and adipose tissue, initiating anabolic cascades independent of upstream hormonal regulation

This hormone, which is the main key to the entry of glucose into target cells (muscle and adipose tissue), in its absence causes the accumulation of glucose in the blood and the development of chronic hyperglycemia [79]